Table 1.
Sample | cRGD contenta (mol %) | Diameterb (nm) | Diameterc (nm) | PDIb | Zeta potentiald (mV) |
---|---|---|---|---|---|
Ctrl-PICsome | 0 | 92 ± 5 | 90 ± 12 | 0.085 | −28 |
20%-cRGD-PICsome | 23.4 | 86 ± 10 | 82 ± 21 | 0.094 | −27 |
40%-cRGD-PICsome | 40.4 | 94 ± 8 | 86 ± 21 | 0.016 | −23 |
100%-cRGD-PICsome | 97.5 | 92 ± 2 | 85 ± 23 | 0.072 | −20 |
The cRGD content was determined using 1H NMR.
The number average diameter, as determined using DLS (n = 10, mean ± s.d., s.d. = standard deviation).
The number average diameter, as determined using TEM (n = 200, mean ± s.d.).
The zeta-potentials were determined using a zetasizer.