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. 2016 Nov 8;6:36719. doi: 10.1038/srep36719

Figure 4.

Figure 4

(a) Typical Cole-Cole plot obtained with PNA-based sensor before and after hybridisation with 1 fM miR-145 (black and blue respectively) and AuNP attachment (pink). A zoom-in version of Cole-Cole plot shows the changes in capacitance upon a molecular binding event. (b) Calibration curve and data points represent average changes in capacitance from a minimum of three independent samples upon binding with AuNPs at different concentration of miR-145.