Skip to main content
. 2016 Oct 21;26(11):1182–1196. doi: 10.1038/cr.2016.118

Figure 3.

Figure 3

Different types of mitochondrial perturbation affect the fitness of animals differently. (A) Lifespan analysis of three independent transgenic lines rab-3p::Cas9+u6p::spg-7-sg, unc-119p::Tom20::KillerRed or unc-119p::ucp-4::mCherry. (B) Oxygen consumption is detected in transgenic strain containing rab-3p::Cas9+u6p::spg-7-sg or unc-119p::Tom20::KillerRed. n ≥ 1 200. (C) Survival analyses of transgenic worms exposed to 25 μg/ml antimycin A is performed as described in the Materials and Methods. n = 30. Error bars indicate mean ± SE. A Student's t-test is used to assess significance: *P < 0.05.