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. 2016 Nov 8;6:36768. doi: 10.1038/srep36768

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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MYO18A is located at the Golgi apparatus through interaction of its PDZ domain with GOLPH3 and Golgin45. It also directly binds F-actin, which is connected to dystrophin. The interaction between MYO18A and p190RhoGEF, as well as Lurap1, regulates the organization of cytoskeleton and Golgi-mediated trafficking. Thus, MYO18A may link the Golgi apparatus to dystrophin through F-actin.