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. 2016 Nov 8;6:36159. doi: 10.1038/srep36159

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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The development of the DN (A), DP (B), SP4 (C), and SP8 (D) thymocyte populations in the pre-natal thymus, simulated by model M1.V1 (continuous line) and model M2.V1 (dotted line). (E) The changes in the whole number of thymocytes in the pre-natal thymus in both models. (F) The dynamics of the thymocyte composition in the pre-natal thymus, in both models. The filled triangles on each chart are the experimental number of thymocytes at the respective time points.