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. 2016 Nov 8;6:36159. doi: 10.1038/srep36159

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(A) The conveyor-belt type, compartmental model of the pre-natal and post-natal thymus, used in our simulations. The stromal component of the thymus surrounds the thymocytes, as it happens in vivo. (B) logistic functions fitted to the number of thymic progenitors in the pre-natal thymus⁶. The vertical, thickened line at 19.5(0) represents the borderline between the end of pregnancy and the beginning of the post-natal life.