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. 2016 Nov 3;2(6):353–358. doi: 10.1192/bjpo.bp.116.003376

Table 2. Association analyses between amygdala activity in the Negative Faces > Shapes contrast and oxytocin receptor polymorphisms.

SNP Amygdala hemisphere SCZ n=104 AD n=100 HC n=142 Total N=346
Effect size P Effect size P Effect size P Effect size P
Rs2254298 (G)a Left b=0.12 0.97 b=−1.35 0.67 b=1.92 0.40 b=0.72 0.66
Right b=−1.11 0.77 b=4.24 0.20 b=0.45 0.84 b=1.22 0.47
Rs53576 (G) Left b=4.93 0.026 b=0.37 0.87 b=−3.36 0.06 b=0.35 0.77
Right b=3.28 0.19 b=0.69 0.77 b=−1.14 0.50 b=0.77 0.54
Rs237902 (G) Left b=−4.99 0.014b b=−0.25 0.90 b=2.81 0.08 b=−0.56 0.59
Right b=−3.84 0.097 b=−2.66 0.18 b=2.65 0.08 b=−1.00 0.36

SNP, single nucleotide polymorphism; SCZ, schizophrenia spectrum disorders; AD, affective spectrum disorders; HC, healthy controls.

a

Results for the G allele dosage are displayed.

b

Remains significant after Bonferroni corrections (3 independent tests).