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. 2016 Nov 8;16:859. doi: 10.1186/s12885-016-2913-x

Table 1.

Physicochemical property of L-BPA and [19F]-L-FBPA

L-BPA [19F]-L-FBPA
Melting point 285–298 °C 266–269 °C
Solubility (water, 25 °C) 1.6 g/L 2.6 g/L
Acid dissociation constant pKa: 2.10 (−COOH) pKa: 2.11 (−COOH)
pKb1: 8.43 (−NH2) pKb1: 7.71 (−NH2)
pKb2: 9.79 (−B(OH)2) pKb2: 9.49 (−B(OH)2)