Table 6.
Correlations between protein expressions (MAPK-1,HIF-1αand HO-1) and coronary angiography indicators among groups of premenopausal and postmenopausal women
| Indicators | Premenopausal-CAD group | Postmenopausal-CAD group | ||||
|---|---|---|---|---|---|---|
| MAPK-1 | HIF-1α (ng/L) | HO-1 (ng/L) | MAPK-1 | HIF-1α (ng/L) | HO-1 (ng/L) | |
| Lesion vessels | ||||||
| Left main coronary artery | 4.4 ± 0.1 | 13.8 ± 4.3 | 230.5 ± 50.2 | 4.7 ± 0.2 | 15.8 ± 4.2 | 264.3 ± 89.8 |
| Anterior descending artery | 4.5 ± 0.1 | 17.2 ± 7.3* | 374.4 ± 195.3* | 4.7 ± 0.12 | 21.4 ± 10.1* | 397.7 ± 159.4* |
| Circumflex coronary artery | 4.5 ± 0.1 | 20.3 ± 11.3@ | 419.6 ± 210.1@ | 4.8 ± 0.1 | 29.9 ± 12.1@ | 482.8 ± 278.4@ |
| Right coronary artery | 4.6 ± 0.2 | 24.1 ± 14.2& | 527.1 ± 273.1& | 4.8 ± 0.1 | 35.9 ± 15.0& | 598.1 ± 262.1& |
| Number of stenosed coronary vessel | ||||||
| Single vessel lesion | 4.5 ± 0.2 | 16.0 ± 3.5 | 283.6 ± 82.0 | 4.7 ± 0.2 | 16.1 ± 3.7 | 278.4 ± 91.7 |
| Double vessel lesion | 4.5 ± 0.1a | 19.3 ± 9.9a | 409.7 ± 175.3a | 4.7 ± 0.1a | 23.6 ± 10.1a | 349.8 ± 183.2a |
| Triple vessel lesion | 4.5 ± 0.2b | 29.1 ± 13.2b | 561.6 ± 280.6b | 4.8 ± 0.1b | 39.6 ± 13.2b | 637.9 ± 257.6b |
| Lesion type | ||||||
| Type A | 4.4 ± 0.2 | 14.7 ± 2.9 | 236.9 ± 90.2 | 4.7 ± 0.1 | 18.7 ± 4.5 | 293.5 ± 85.4 |
| Type B | 4.5 ± 0.1c | 17.6 ± 8.1c | 418.7 ± 161.3c | 4.7 ± 0.1c | 25.1 ± 7.9c | 375.8 ± 155.5c |
| Type C | 4.6 ± 0.2d | 30.7 ± 11.4d | 520.6 ± 224.5d | 4.8 ± 0.2d | 34.7 ± 10.8d | 614.5 ± 249.5d |
*: compared with left main coronary artery; @: compared with anterior descending artery; &: compared with circumflex coronary artery; a: compared with single vessel lesion; b: compared with double vessel; c: compared with type A; d: compared with type B