Fig. 2.

The anti-metastasis activity of miR-193a in lung cancer cells. a and b Transwell migration (a) and invasion (b) assays were performed in A549 and H1299 cells transfected with lentivirus LVX-miR-193a or negative control LVX-NC. *P < 0.01 versus NC. c and d Wound healing assay was measured in A549 (c) and H1299 cells (d), which were transfected with LVX-miR-193a or LVX-NC. *P < 0.01 versus NC. e Colony formation was performed by methylene blue staining in A549 and H1299 cells transfected with LVX-miR-193a or LVX-NC. *P < 0.01 versus NC. f Cell proliferation was detected by CCK-8 assay in A549 and H1299 cells transfected with LVX-miR-193a or LVX-NC for 24, 48, and 72 h. Scale bar = 50 μm. The results are representative of at least three independent experiments. Statistical analysis was performed using Student’s t-test