Table 1.

Comparison of binding energy components between RRM domain and RNA in 3 complex systems.

TYPE	ΔEvdwa	ΔEelec	ΔGpolar	ΔGnonpolar	ΔGbinding
Complex-WT	−43.01 ± 3.68	−234.96 ± 22.12	132.62 ± 23.59	−4.89 ± 0.40	−150.25 ± 14.02
Complex-R38Q	−45.52 ± 4.90	−215.22 ± 25.93	134.95 ± 29.95	−5.28 ± 0.59	−131.07 ± 14.78
Complex-T103A/K104A	−27.27 ± 6.51	−182.70 ± 26.25	111.02 ± 26.77	−3.40 ± 0.72	−102.35 ± 15.38

^aΔE_vdw, ΔE_elec, ΔG_polar, andΔG_nonpolar are binding energy components of van der Waals, electrostatic, polar and nonpolar solvation energies, respectively. ΔG_binding is the total binding energy. The energies are in kilocalories per mole.