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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: Mamm Genome. 2016 May 23;27(9-10):495–502. doi: 10.1007/s00335-016-9644-9

Fig. 3.

Fig. 3

Nebulin is drastically reduced in skeletal muscles with S8042X. a Protein analysis on a 2–7 % gradient acrylamide gel reveals a clear loss of nebulin in muscles from affected dogs compared to healthy controls. b Western blots for the same samples using antibodies to nebulin’s N- and C-terminus. c and d Average quantification (CTRL 1 and CTRL 2; AFF 1 and AFF 2) of western blots, indicating a severe loss of nebulin protein in affected dogs.