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. 2016 Nov 8;9:117. doi: 10.3389/fnmol.2016.00117

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Copyright © 2016 Song, Sun, Liu, Chen, Zhang, Wang, Mo, Che, Ouyang, Yuan and Fan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Histology images stained with toluidine blue and transmission electron microscopy (TEM) micrographs. Images represent cross sections of regenerated nerves taken from different conduits in rats at 8 weeks post-implantation. (A,D,G) From the PPY/PLCL group, (B,E,H) from the PPY/PLCL + ES group and (C,F,I) from the autograft group. Histology scale bar: 50 μm (A–C). TEM scale bar: 5 μm (D–F), 500 nm (G–I). (J) Average axon diameter. (K) Nerve fiber diameter. (L) Number of nerve fibers. (M) Thickness of myelin sheath (n = 5, ^#p < 0.05 the PPY/PLCL + ES group vs. PPY/PLCL group; *p < 0.05, **p < 0.01 the autograft group vs. PPY/PLCL group; ^δp < 0.05, the autograft group vs. PPY/PLCL + ES group).