Table 1. Summary of administration errors.
Wk 1 (n = 96)a | Wk 2 (n = 90)a | Wk 3 (n = 94)a | Wk 4 (n = 88)a | Wk 5 (n = 91)a | Wk 6 (n = 93)a | Wk 7 (n = 92)a | Wk 8 (n = 92)a | |
---|---|---|---|---|---|---|---|---|
Use errors, n (%) | ||||||||
Any use error | 1 (1) | 1 (1) | 2 (2) | 1 (1) | 1 (1) | 3 (3) | 4 (4) | 1 (1) |
Autoinjector not properly activated on injection site | 1 (1)b | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Autoinjector pulled away before end of injection | 0 | 1 (1) | 1 (1)b | 0 | 1 (1) | 1 (1) | 1 (1)b | 1 (1) |
Medication observed at the injection site | 0 | 0 | 1 (1) | 1 (1) | 0 | 2 (2) | 3 (3) | 0 |
Device error, n (%) | ||||||||
Any device error | 0 | 0 | 0 | 0 | 1 (1) | 1 (1) | 2 (2) | 0 |
Delivery stopped before end of injection | 0 | 0 | 0 | 0 | 1 (1)b | 0 | 0 | 0 |
Autoinjector did not activate | 0 | 0 | 0 | 0 | 0 | 0 | 1 (1)b | 0 |
Autoinjector leaked | 0 | 0 | 0 | 0 | 0 | 1 (1)c | 1 (1)c | 0 |
aNumber of injection attempts. In 5 cases, a patient had 2 attempts to administer their dose; bthe first attempt at injection was unsuccessful, the second attempt was successful; c1 patient reported unsuccessful injections at week 6 and 7, which were initially attributed to both use error and device error; further investigation determined that the injections were unsuccessful due to use error only.