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. 2016 Nov 8;3:160100. doi: 10.1038/sdata.2016.100

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0 Metadata associated with this Data Descriptor is available at http://www.nature.com/sdata/ and is released under the CC0 waiver to maximize reuse.

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PyKNOSSOS running on a local machine streams cubed image data from a web server (data store; NeuroData) and stores cubes on disk. Cubes are generated by NeuroData and dynamically loaded into PyKNOSSOS. Annotations (e.g., skeleton reconstructions) are downloaded from a repository (label store) and may be modified locally.