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. 2016 Sep 28;6(11):7448–7451. doi: 10.1021/acscatal.6b02114

Table 1. Preparation of α-Allenols from Propargyl Substrates with Acetate and Protected Hydroxyl on Opposite Sides of the Alkynea.

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a

Isolated yields. Conditions: 0.1 M solution of substrate 1 (1 equiv), R4 MgX (1.25 equiv), and 1 mol % of Fe(acac)3 in Et2O, addition of R4 MgX for 5 and 10 min reaction time.

b

R4 MgX (1.5 equiv), 5 mol % of Fe(acac)3.

c

R4 MgX (1.75 equiv), 7.5 mol % of Fe(acac)3.

d

R4 MgX (1.75 equiv), 5 mol % of Fe(acac)3.

e

5 mol % of Fe(acac)3.

f

R4 MgX (2 equiv), 7.5 mol % of Fe(acac)3.