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. Author manuscript; available in PMC: 2017 Oct 19.
Published in final edited form as: Bioconjug Chem. 2016 Sep 14;27(10):2407–2417. doi: 10.1021/acs.bioconjchem.6b00377

Figure 4.

Figure 4

Blood clearance profiles, biodistribution and urine analysis for probes 1, 3, 4 and 5 in C57BL/6 (n=3 for each probes, 1 nmol injected). (A) Comparison of blood clearance rates between the four probes (1: black circles, 3: black diamonds, 4: black squares and 5: empty triangles). (B) Biodistribution and fluorescence intensity patterns observed for probes 1, 3, 4 and 5 in liver, spleen, kidneys and lungs harvested 4h after injection. Fluorescence is expressed as arbitrary units (AU). (C) Analyses by LC/MS of mouse urines at 4h after injection in the case of probes 1, 3 and 4.