Table 1.
Characteristics of Included Studies
| Study USPSTF Quality Rating | Design | Country | Patients/Exams Analyzed | Follow-Up Period | Population Characteristics |
|---|---|---|---|---|---|
|
Breast Imaging-Reporting and Data System (BI-RADS) Density Assessment | |||||
| Harvey, 2013 (20) Good |
Cohort | United States | 871,502 exams 435,751 women | <36 moa | Age: 58.8y (mean) |
| Redondo, 2012 (21) Good |
Stratified random sample | Spain | 100 exams 100 women |
6 moa | Age: 50–64y (range) |
| Spayne, 2012 (22) Good |
Cohort | United States | 11,755 women | 3–24 moa | Age: 66y (median) |
| Bernardi, 2012 (23) Fair |
Test set | Italy | 100 exams 100 women |
NA | Age: 43y (median) |
| Gard, 2015 (24) Fair |
Test set | United States | 341 women | 6 moa | NR |
|
Hand-Held Ultrasound (HHUS) | |||||
| Berg, 2012 (25) Good |
Test accuracy | United States | 3,414 exams 1,216 women |
≥12 mo | Age: 55.2y (mean)* Dense breasts: 100% Personal hx: 0% Family hx: NR |
| Corsetti, 2011 (26) Good |
Test accuracy | Italy | 7,224 exams 3,356 women |
12 mo | Age: 55% <50y Dense breasts: 100% Personal hx: NR Family hx: NR |
| Brancato, 2007 (27) Fair |
Cohort | Italy | 5,227 women | NR | Age: 68% 40–49y Dense breasts: 100% Personal hx: NR Family hx: NR |
| Girardi, 2013 (28) Fair |
Cohort | United States | 9,960 women | 12 mo | Age: 51.2y (mean)* Dense breasts: 100% Personal hx: 9.8% Family hx: NR |
| Hooley, 2012 (29) Fair |
Test accuracy | United States | 648 women | ≥15 mo | Age: 52y (mean)* Dense breasts: 100% Personal hx: NR Family hx: NR |
| Leong, 2012 (30) Fair |
Test accuracy | Singapore | 106 women | 12–24 mo | Age: 45.1y (mean) Dense breasts: 100% Personal hx: 5% Family hx: 20.9% |
| Parris, 2013 (31) Fair |
Cohort | United States | 5,519 women | NR | Age: 53.6y (mean) Dense breasts: 89% Personal hx: 6% Family hx: 42% |
| Venturini, 2013 (32) Fair |
Cohort | Italy | 826 women | NR | Age: 100% <50y * Dense breasts: 100% Personal hx: NR Family hx: 24%* |
| Weigert, 2012 (33) Fair |
Cohort | United States | 8,647 exams 8,647 women |
NR | Age: 54.4y (mean) Dense breasts: 100% Personal hx: NR Family hx: NR |
| Youk, 2011 (34) Fair |
Test accuracy | South Korea | 446 exams | 24 mo | Age: 47.5y (mean)* Dense breasts: 100% Personal hx: 0% Family hx: NR |
|
Automated Whole Breast Ultrasound (ABUS) | |||||
| Brem, 2015 (35) Fair |
Cohort | United States | 15,318 | 12 mo | Age: 53.3y (mean) Dense breasts: 100% Personal hx: 3.6% Family hx: 44.8% |
| Giuliano, 2013 (36) Fair |
Cohort | United States | 3,418 women | 12 mo | Age: NR Dense breasts: 100% Personal hx: 0% Family hx: 0% |
| Kelly, 2010 (37) Fair |
Test accuracy | United States | 6,425 exams 4,419 women |
12 mo | Age: 53y (mean)* Dense breasts: 68% Personal hx: 10%* Family hx: : 30% |
|
Magnetic Resonance Imaging (MRI) | |||||
| Berg, 2012 (25) Good |
Test accuracy | United States | 334 exams | 12 mo | Age: 56.8y (mean) Dense breasts: 100% Personal hx: NR Family hx: NR |
| Kriege, 2006 (38) Good |
Test accuracy | Netherlands | 1,723 exams | 12 mo | Age: 40y (mean)* Dense breasts: 100% Personal hx: NR Family hx: 100% |
| Kuhl, 2014 (39) Good |
Test accuracy | Germany | 105 women | 24 mo | Age: 53.2y (mean) Dense breasts: 100% Personal hx: NR Family hx: NR |
|
Digital Breast Tomosynthesis (DBT) | |||||
| Ciatto, 2013 (40) Fair |
Cohort | Italy | 1,215 women | No follow-up except on biopsy results | Age: 58y (median)* Dense breasts: 100% Personal hx: NR Family hx: NR |
| Haas, 2013 (41) Fair |
Cohort | United States | 4,794 exams | No follow-up except on biopsy results | Age: 33.3% <40y* Dense breasts: 100% Personal hx: 5.5%* Family hx: NR |
| McCarthy, 2014 (42) Fair |
Cohort | United States | 8,545 exams | No follow-up except on biopsy results | Age: 70% >50y Dense breasts: 100% Personal hx: NR Family hx: NR |
| Rose, 2013 (43) Fair |
Cohort | United States | 11,675 exams | No follow-up except on biopsy results | Age: 54.2y (mean)* Dense breasts: 100% Personal hx: NR Family hx: NR |
a
time between mammographic assessments
*
Data is reflective of the entire study population, not necessarily the subgroup with dense breasts
Abbreviations: Hx = history; mo=months; NA=not applicable; NR=not reported; y=years