Table 2. LET-23 EGFR and LET-60 Ras induce ectopic uv1 specification.
| Genotype | No. of GFP-Positive uv1 Cells | Average No. of uv1 Cells Specified | n | |||
|---|---|---|---|---|---|---|
| 7 | 6 | 5 | 4 | |||
| Wild-type (strain BL5715) | 0 | 0 | 0 | 60 | 4 | 60 |
| let-23(sa62gf) (strain HV760) | 0 | 1 | 8 | 49 | 4.17* | 58 |
| let-60(n1046gf) (strain HV285) | 1 | 29 | 55 | 51 | 4.85*** | 136 |
| itr-1(sy290gf) (strain HV651) | 0 | 0 | 0 | 111 | 4 | 111 |
| let-60(n1046gf) itr-1(sy290gf) (strain HV623) | 1 | 38 | 71 | 19 | 5.16**,*** | 129 |
n, number of animals examined.
P < 0.005.
P < 0.001, Student’s t-test, comparison to let-60(n1046gf).
P < 0.001, Student’s t-test, comparisons to wild type.