Table 1. Spontaneous mutational spectrum of HAdv5.

Mutation	Replicate assay			Total %
	1	2	3
G→A	11	22	13	22.1
C→T	13	13	17	20.7
A→G	9	17	6	15.4
T→C	6	5	7	8.7
G→T	8	2	1	5.3
C→A	8	5	4	8.2
T→G	2	3	3	3.8
A→C	2	2	3	3.4
G→C	2	4	3	4.3
C→G	2	2	1	2.4
A→T	4	1	1	2.9
T→A	1	2	3	2.9
Total	68	78	62	100.0
Mbp sequenced	93.2	115.7	123.7	-
Mutation frequency (× 106)	0.73	0.67	0.50	-