Fig 2. The murine PC-3 and LNCaP xenografts were treated with sarcosine i.p.

(A) Schematic depiction of experimental workflow beginning with the PCa cells (5×10⁶) s.c. inoculation. (B) Average weight of mice determined after the termination of experiment. (C) Selected photographs of excised ectopic prostate tumors treated with sarcosine (left) and non-treated after termination of the experiment (right). (D) Average tumor weight at the endpoint of the experiment. Values are expressed as the means ± standard deviations of three independent replicates (n = 3). Vertical bars indicate standard error. Asterisks indicate significant differences (p < 0.05) compared to the untreated group. (E) H&E-stained tissue sections of ectopic prostate tumors after treatment with sarcosine (left) and non-treated (right). The length of scale bar is 100 μm.