Table 1. Baseline Characteristics of Study Cohort in 1986 According to Smoking Status and Alcohol Consumption.
| Smoking status | Alcohol Consumption (g/day) | |||||||
|---|---|---|---|---|---|---|---|---|
| Never | Past | Current | 0 | 1–4 | 5–14 | 15–29 | ≥30 | |
| (n = 21627) | (n = 19987) | (n = 4517) | (n = 10569) | (n = 10954) | (n = 12398) | (n = 6012) | (n = 5333) | |
| Age, years | 52.7(9.8) | 55.7(9.7) | 53.8(9.2) | 54.2(9.9) | 53.2(9.9) | 53.6(9.6) | 53.7(9.4) | 55.3(9.5) |
| Body mass index, kg/m2 | 25.3(3.3) | 25.8(3.3) | 25.4(3.2) | 25.7(3.6) | 25.6(3.3) | 25.4(3.1) | 25.3(3.0) | 25.5(3.2) |
| Physical activity, MET h/wk | 21.7(29.4) | 21.2(29.6) | 15.3(23.1) | 18.8(27.0) | 20.2(26.7) | 22.6(30.2) | 24.0(34.5) | 21.1(29.5) |
| NSAID use (%)a | 8.2 | 11.1 | 11.1 | 8.5 | 9.1 | 9.7 | 11.3 | 12.4 |
| Aspirin use (%)a | 27.5 | 33.3 | 31.6 | 26.6 | 26.6 | 30.3 | 32.5 | 34.3 |
| Cardiovascular disease (%) | 3.4 | 5.9 | 4.8 | 4.9 | 4.9 | 4.3 | 3.7 | 4.1 |
| Osteoarthritis (%) | 8.3 | 9.3 | 8.9 | 8.5 | 8.2 | 8.4 | 8.8 | 9.9 |
| Alcohol, g/day | 8.0(12.2) | 13.6(16.4) | 17.5(20.4) | |||||
| Smoking status (%) | ||||||||
| Never | 61.4 | 52.6 | 44.2 | 36.8 | 25.3 | |||
| Past | 31.7 | 39.7 | 46.7 | 53.5 | 54.2 | |||
| Current | 6.9 | 7.6 | 9.1 | 9.7 | 20.6 | |||
NOTE: All values are means (SD) or percentages. All variables except age are standardized to the age distribution of the study population. MET, metabolic equivalent; NSAID, nonsteroidal anti-inflammatory drug.
a NSAID and aspirin use defined as regular use at least 2 times per week