Skip to main content
. 2016 Nov 8;11(11):e0166085. doi: 10.1371/journal.pone.0166085

Table 3. Performance parameters of scoring system as predictors of short-term and long-term mortality of critically ill subjects.

Models auROC (95%) P Cut-Off Point Se (%) Sp (%) +LR -LR +PV -PV
Training cohort (30-day)
    GV-SAPS II 0.825 (0.814–0.835) < 0.001 28 75.94 73.23 2.84 0.33 28.8 95.5
    SAPS II 0.796 (0.784–0.807) < 0.001 38 74.63 71.15 2.59 0.36 27 95.2
    SOFA 0.790 (0.778–0.801) < 0.001 5 64.32 78.41 2.98 0.46 29.8 93.9
    Elixhauser score 0.720 (0.708–0.733) < 0.001 0 68.9 66.9 2.08 0.46 22.9 93.8
Training cohort (9-month)
    GV-SAPS II 0.764 (0.752–0.776) < 0.001 26 71.33 67.55 2.2 0.42 33.5 91.1
    SAPS II 0.740 (0.728–0.752) < 0.001 32 77.46 59.98 1.94 0.38 30.8 92.1
    SOFA 0.717 (0.705–0.730) < 0.001 5 51.86 78.8 2.45 0.61 36 87.7
    Elixhauser score 0.722 (0.710–0.735) < 0.001 0 67.18 69.23 2.18 0.47 33.4 90.2
Validation cohort (30-day)
    GV-SAPS II 0.824 (0.813–0.834) < 0.001 26 77.91 71.11 2.7 0.31 22.4 96.8
    SAPS II 0.793 (0.782–0.804) < 0.001 33 83.64 64.69 2.37 0.25 20.3 97.4
    SOFA 0.772 (0.760–0.783) < 0.001 5 55.01 83.4 3.31 0.54 26.2 94.5
    Elixhauser score 0.724 (0.712–0.736) < 0.001 3 65.44 68.87 2.1 0.5 18.4 94.9
Validation cohort (9-month)
    GV-SAPS II 0.738 (0.725–0.750) < 0.001 24 70.61 63.25 1.92 0.46 26.7 91.9
    SAPS II 0.722 (0.710–0.735) < 0.001 29 79.83 56.28 1.83 0.36 25.7 93.6
    SOFA 0.674 (0.661–0.687) < 0.001 6 31.76 91.33 3.66 0.75 40.9 87.6
    Elixhauser score 0.724 (0.712–0.737) < 0.001 3 64.26 71.19 2.23 0.5 29.7 91.3

NOTE. Se, sensitivity; Sp, specificity; +LR, positive likelihood ratio; -LR, negative likelihood ratio; +PV, positive predictive value; -PV, negative predictive value; CI, confidence interval.