Table 4. Significant independent predictors of OS and LFS in IPSS-R High and Very High risk patients (n = 260).

Variables	HR for OS (95% CI)	p-value	HR for LFS (95% CI)	P-value
Translocation
No	1		1
Yes	1.72 (1.08–2.73)	0.02	1.65 (1.04–2.60)	0.03
CK
No	1		1
Yes	1.77 (1.22–2.57)	< 0.01	1.48 (0.98–2.23)	0.06
HSCT
No	1		1
Yes	0.26 (0.15–0.45)	< 0.01	0.23 (0.14–0.40)	<0.01

Abbreviations: HR, hazard ratio; CI, confidence interval; OS, overall survival; IPSS-R, revised International Prognostic Scoring System; CK, complex karyotype; HSCT, hematopoietic stem cell transplantation.