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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: Semin Hematol. 2016 Jul 25;53(4):230–236. doi: 10.1053/j.seminhematol.2016.07.003

Table 3.

Donor-recipient mismatching at certain amino acid residues is permissive.

Mismatched
HLA Locus
GVHD Relapse Survival
HLA-A None identified22;
Residue 9 [aGVHD23]
None
identified22
None identified22
HLA-B Residue 9 [cGVHD22] None identified22 None identified22
HLA-C Residue 116 [aGVHD22];
Residues 9, 77, 80, 99, 116,
156 [aGVHD23]
Residues 9, 99, 156
24
Residue 99 [TRM
22]
HLA-DPB1 TCE model [aGVHD9] *GVL24;
*TCE model9
No [GVH and GVL
balanced9]

aGVHD, acute GVHD

cGVHD, chronic GVHD

*

Different eptiopes were tested9, 24