Table 2.
| a: Time invariant characteristics |
Overall (baseline) |
HIV + | Remained HIV− | Unadjusted HR (95%CI) | |
|---|---|---|---|---|---|
| Control | 589 (49.1%) | 150 | 385 | Ref | |
| Intervention | 611 (51.0%) | 94 | 456 | 0.53 (0.37,0.76) p=0.0006 | |
| City | |||||
| Odessa | 421 (35.1%) | 98 | 299 | 0.96 (0.62, 1.51) p=0.87 | |
| Donetsk | 363 (30.3%) | 93 | 214 | Ref | |
| Nikolayev | 416 (34.7%) | 53 | 328 | 0.36 (0.23, 0.56) p<0.0001 | |
| Sex | |||||
| Male | 899 (74.9%) | 179 | 630 | Ref | |
| Female | 301 (25.1%) | 65 | 211 | 1.28 (0.92, 1.80) p=0.15 | |
| b: Time Varying Exposures |
Overall (baseline) |
HIV + | Remained HIV− | Unadjusted HR (95%CI) | |
|---|---|---|---|---|---|
| Mean Age (sd) | 31.81 (8.36) | 35.02 (7.72) | 31.73 (8.48) | 1.05 (1.03, 1.07) p =0.0016 | |
| Daily Injector | |||||
| yes | 520 (43.3%) | 120 | 310 | 1.50 (1.11, 2.02) p=0.007 | |
| no | 680 (56.7%) | 128 | 523 | Ref | |
| Always Inject with others | |||||
| yes | 584 (48.7%) | 99 | 326 | 1.00 (0.75, 1.30) p=0.92 | |
| no | 616 (51.3%) | 149 | 507 | Ref | |
| Mean Years of injecting (sd) |
11.65 (8.97) | 14.88 (8.34) | 11.54 (9.16) | 1.05 (1.03, 1.07) p<0.0001 | |
| Log Injection frequency mean (sd) |
3.04 (0.89) | 3.11 (1.20) | 2.92 (1.01) | 1.10 (1.04, 1.16) p=0.0004* | |
| Common Container (N=1199) |
|||||
| Yes | 464 (38.7%) | 94 | 332 | 1.06 (0.77, 1.45) p=0.74 | |
| no | 735 (61.3%) | 154 | 500 | Ref | |
| Front and Back Loading with others |
|||||
| Yes | 863 (71.9%) | 198 | 605 | 1.59 (1.11, 2.28) p=0.012 | |
| No | 337 (28.1%) | 50 | 227 | Ref | |
| Front back loading with dealer and/ or others |
|||||
| Yes | 1162 (96.8%) | 242 | 799 | 6.20 (1.45, 26.5.9) p=0.014 | |
| No | 38 (3.2%) | 6 | 34 | Ref | |
| Shared Works (N=1199) | |||||
| Yes | 341 (28.4%) | 88 | 274 | 1.42 (1.02, 2.00) p=0.04 | |
| No | 858 (71.6%) | 160 | 559 | Ref | |
| Mean overall drug risk score (sd) |
1.59 (0.90) | 1.57 (0.94) | 1.52 (0.89) | 1.13 (0.95, 1.33) p=0.18 | |
| More than one sexual partner (N=1194) |
|||||
| Yes | 267 (22.3%) | 157 | 673 | 0.61 (0.45, 0.84) p=0.003 | |
| No | 927 (77.6%) | 91 | 160 | Ref | |
| Unprotected Sex (N=1180) |
|||||
| Yes | 481(41.0%) | 87 | 292 | 1.07 (0.80, 1.43) p=0.63 | |
| No | 699 (59.3%) | 161 | 536 | Ref | |
| Sex with an injection drug user (N=1185) |
|||||
| Yes | 493 (41.6%) | 105 | 399 | 0.92 (0.67, 1.25) p=0.59 | |
| No | 692 (58.4%) | 141 | 424 | ref | |
| Sex with HIV positive | |||||
| Yes | 31 (2.6%) | 11 | 22 | 1.05 (0.43, 2.54) p=0.92 | |
| No | 1169 (97.4%) | 237 | 811 | ref | |
| Sex for trade (N=1197) | |||||
| Yes | 25 (2.1%) | 3 | 20 | 0.88 (0.32, 2.43) p=0.81 | |
| No | 1172 (97.9%) | 245 | 813 | ref | |
a) Time invariant characteristics are presented for final visit. Totals will not sum to total baseline numbers due to follow up. Total denominator is 1200 unless otherwise reported.
b) Time varying exposures are presented for 6 month visit to parallel the lagged cox regression analysis. Injection frequency is right tailed and log transformed.
*
per 10 injections