Fig. 6.

(a) The layout of the cored specimens (S1–S7) demonstrated on a proximal femur image. Three-dimensional visualization of the average (b) modulus (E) with the upper and lower limits of data at each site; and (c) bone volume fraction (BV/TV) distribution of human proximal femur. In (a), sites S1, S4, S6, and S7 form a loop or belt from the femoral head, through the neck and onto the trochanteric region, where the applied load (in a relatively uniform magnitude) traverses through the proximal femur and disburses into the cortical shaft. It is possible that the loads resultant from normal daily activities are mostly translated though this loop, whereas sites S2 and S3 encounter the higher loads applied to the proximal femur for higher impact activities. (From Reference 117 with permission.)