Table 4.
Major osteoporotic fractures
|
Hip fractures
|
|||||
---|---|---|---|---|---|---|
HR | 95% CI | p | HR | 95% CI | p | |
Sex (women vs. men) | 1.20 | 0.96–1.50 | 0.10 | 0.55 | 0.37–0.82 | <0.01 |
Age (per 10 years) | 1.33 | 1.20–1.46 | <0.001 | 2.02 | 1.65–2.48 | <0.001 |
BMI (per 5 kg/m2) | 1.14 | 1.04–1.24 | <0.01 | 1.00 | 0.82–1.20 | 0.97 |
Prior fragility fracture | 1.61 | 1.31–1.97 | <0.001 | 1.89 | 1.31–2.75 | <0.001 |
Parental hip fracture | 0.92 | 0.69–1.23 | 0.58 | 1.14 | 0.67–1.96 | 0.63 |
Rheumatoid arthritis | 1.63 | 0.81–3.25 | 0.17 | 1.50 | 0.43–5.17 | 0.52 |
Corticosteroid use | 0.72 | 0.37–1.38 | 0.32 | 0.71 | 0.24–2.07 | 0.53 |
Smoking | 1.03 | 0.81–1.30 | 0.81 | 1.51 | 0.98–2.31 | 0.06 |
Alcohol use >2 U/day | 0.80 | 0.43–1.52 | 0.50 | 0.82 | 0.26–2.61 | 0.73 |
Femoral neck T-score (per SD decrease) | 1.56 | 1.42–1.71 | <0.001 | 1.96 | 1.62–2.37 | <0.001 |
Data are from Cox proportional hazards models