Table 2.
Year of CaMos study | Incident fracture rate n (%) | Any osteoporosis therapya
|
Bisphosphonate therapy
|
Hormone therapy
|
|||
---|---|---|---|---|---|---|---|
OR | 95%CI | OR | 95%CI | OR | 95%CI | ||
2 | 128 (2.4) | 1.15 | 0.66–2.00 | 1.69 | 0.90–3.2 | 0.82 | 0.45–1.52 |
3 | 107 (2.1) | 0.95 | 0.53–1.73 | 1.74 | 0.88–3.42 | 0.60 | 0.35–1.04 |
4 | 94 (1.9) | 1.42 | 0.77–2.61 | 2.72 | 1.31–5.62 | 0.68 | 0.33–1.41 |
5 | 125 (2.6) | 1.09 | 0.64–1.84 | 1.90 | 0.97–3.70 | 0.60 | 0.32–1.11 |
6 | 104 (2.4) | 1.21 | 0.70–2.10 | 2.25 | 1.19–4.27 | 0.76 | 0.43–1.35 |
7 | 90 (2.1) | 1.51 | 0.85–2.69 | 3.57 | 1.79–7.15 | 0.27 | 0.10–0.72 |
8 | 94 (2.3) | 1.67 | 0.94–2.98 | 3.94 | 1.99–7.80 | 0.28 | 0.11–0.70 |
9 | 112 (2.9) | 1.50 | 0.88–2.55 | 4.14 | 2.21–7.74 | 0.15 | 0.06–0.36 |
10 | 104 (2.8) | 1.16 | 0.65–2.07 | 3.65 | 1.83–7.26 | 0.07 | 0.02–0.24 |
Hormone therapy, calcitonin, SERM, or bisphosphonate
OR controlled for BMD, age, smoking, and early menopause (younger than 45) status