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. Author manuscript; available in PMC: 2017 Dec 15.
Published in final edited form as: Int J Cardiol. 2016 Oct 8;225:371–380. doi: 10.1016/j.ijcard.2016.10.021

Figure 2.

Figure 2

AAV9 vector used to overexpress JPH2 in mouse hearts. (A) Junctophilin-2 (AAV9-JPH2) AAV9 vector featuring a cardiac-specific MLC2v800 promoter, N-terminal hemagglutinin (HA) tagged-JPH2, with polyA tail and inverted tandem repeats (ITR). The control (AAV9-Con) vector contains the same elements except for the HA-JPH2 sequence. (B) Representative Western blot showing JPH2 protein levels in ventricular lysates from WT mice transduced with 1×1011 genome-containing units (GCU) by tail vein injection of AAV9-Con or AAV9-JPH2. (C) Quantification of JPH2 protein levels. Number in bars= number hearts.