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. Author manuscript; available in PMC: 2017 Dec 15.
Published in final edited form as: Int J Cardiol. 2016 Oct 8;225:371–380. doi: 10.1016/j.ijcard.2016.10.021

Figure 8.

Figure 8

AAV9-JPH2 increases JPH2 levels in TAC mice and ameliorates downstream hypertrophic responses. (A) Representative images and (B) quantification of Western blots of JPH2 protein levels in heart lysates from sham, and AAV9-Con or AAV9-JPH2 treated TAC mice. GAPDH was used as a loading control. (C) Quantitative polymerase chain reaction (qPCR) analysis of pro-hypertrophic genes including regulator of calcineurin-1 isoform 4 (Rcan1.4), (D) (β-myosin heavy chain (Myh7), (E) atrial natriuretic factor (Nppa), and (F) brain natriuretic peptide (Nppb) normalized to L7 control Numbers in each bar = number of hearts. *P<0.05, **P<0.01 sham vs TAC; #P<0.05, ##P<0.01 AAV9-Con vs AAV9-JPH2.