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. Author manuscript; available in PMC: 2017 Oct 15.
Published in final edited form as: J Immunol. 2016 Sep 21;197(8):3076–3085. doi: 10.4049/jimmunol.1600197

Fig. 5. RAGE+ CD8+ T cells express higher amounts of inflammatory and effector memory markers in T1D patients.

Fig. 5

(A) Expression of EOMES and KLRG1 in RAGE+ and RAGE- CD8+ T cells from a patient with T1D. Data from a single patient representative of 8 is shown. (A–F) EOMES (A), KLRG1 (B), IRF4 (C), and CXCR3 (D), STAT3 (E) levels in RAGE+ (open symbols) and RAGE- (closed symbols) CD8+ T cells from patients with T1D. Each symbol represents a single patient. The graphs display mean fluorescence intensity (MFI) of each marker. Statistical significance was calculated with a nonparametric Wilcoxon signed-rank test for all experiments (**<0.01, *<0.05, mean±SEM). (F,G) The frequency of EOMES/KLRG1 dual+ cells is also shown (**p<0.01).