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. Author manuscript; available in PMC: 2017 Oct 15.
Published in final edited form as: J Immunol. 2016 Sep 12;197(8):2992–3007. doi: 10.4049/jimmunol.1500411

Figure 8. Pretreatment with the “IFN-β + MOG in Alum” vaccine inhibited the subsequent induction of EAE in MOG35-55 TCR transgenic mice.

Figure 8

Vaccines comprised of “MOG35-55 in Alum”, “IFN-β + OVA323-339 in Alum”, or “IFN-β + MOG35-55 in Alum” were given on days −21, −14, and −7 to 2D2-FIG mice at dosages of 5 nmoles for both IFN-β and antigen. Mice were challenged with 100 µg MOG35-55 in CFA on day 0, were given Pertussis toxin on days 0 and 2. The timecourses for EAE (A) and body weight (B) are shown through day 22. Error bars represent standard error of the mean. The statistical analysis is given in Table 2.