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. Author manuscript; available in PMC: 2017 Oct 15.
Published in final edited form as: J Immunol. 2016 Sep 12;197(8):2992–3007. doi: 10.4049/jimmunol.1500411

Figure 9. Does IFN-β adjuvant promote infectious tolerance?

Figure 9

Mice were vaccinated once with three different vaccines including “IFN-β + OVA + MOG in Alum”, “IFN-β + OVA in Alum”, and “OVA in Alum” (5 nmole dose for all reagents) on day −8. Mice were challenged with two different emulsions to induce EAE, including “OVA + MOG in CFA” or “MOG in CFA” (100 µg dose for each peptide) on day 0. Pertussis toxin was given on days 0 and 2. Shown are the timecourse data through day 34 for EAE (A, C) and weight loss (B, D). Statistical analyses are given in Table 3.