Organization of the KMN Network, Related to Figure 1
(A) Drawing of the KMN network and its interaction with CCAN. CH, Calponin-homology domain; RWD, RING finger, WD repeat, DEAD-like helicases.
(B) Schematic representation of the organization of subunits of the KMN network and main functional domains; CC, coiled-coil; N, N-terminal tail (involved in microtubule binding); PEST, proline-glutamic-serine-threonine. The CENP-C motif and the central region of CENP-C contain conserved nucleosome binding motifs.