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Anxiety-like behavior in BIG, SMALL and Control strains. The data represent the mean (± SEM) for (A) time spent on center in open field and (B) total number of line crossings and (C) time spent on open arm in elevated plus maze of the two replicates of the BIG, SMALL and Control strains. ***(p < 0.0001) and *(p < 0.05) indicates significant differences between sham and OVX groups. ###(p < 0.0001) indicate significant differences between replicate strains.
