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. 2016 Nov 9;7:1802. doi: 10.3389/fmicb.2016.01802

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Copyright © 2016 Dahlin, Srivastava, Bulone and McKee.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Enzymatic cyclisation of 2,3-oxidosqualene (OS) to lanosterol (LA) and cycloartenol (CA). Oxidosqualene cyclase enzymes (OSC) protonate the OS substrate, leading to the production of LA or CA.