Table 1.
Frequently used conditioning regimens in various transplant centers worldwide.
| Intensity | Regimen | Comments |
|---|---|---|
| Myeloablative | CY/TBI | Profound pancytopenia, require stem cell support, substantial non-hematological toxicities |
| BU/CY | ||
| Non-myeloablative | FLU/TBI | Minimal cytopenia, do not require stem cell support |
| TLI/ATG | ||
| Low dose TBI | ||
| Reduced intensity | FLU/MEL | Intermittent cytopenia, reduced non-hematological toxicities |
| FLU/BU | ||
| FLU/CY |
CY, cyclophosphamide; TBI, total body irradiation; BU, busulfan; FLU, fludarabine; TLI, total lymphoid irradiation; ATG, antithymocyte globulin; MEL, melphalan.