Table 3.

Comparison of hematopoietic stem cell sources.

Stem cell source	Benefits		Drawbacks
	Donor	Recipient	Donor	Recipient
BM		Lower risk of GvHD	More invasive HSC collection
PBSC	No general anesthesia for collection; less discomfort and pain	Faster hematopoietic engraftment and immune reconstitution; enhanced GvL effect		Higher risk of GvHD
CB	Non-invasive	Lower risks of GvHD and relapse; rapid availability; increased level of HLA-disparity tolerated		Lower number of HSCs; slower immune reconstitution

BM, bone marrow; PBSC, peripheral blood stem cells; CB, cord blood; GvHD, graft-versus-host disease; HSC, hematopoietic stem cell; GvL, graft-versus-leukemia, HLA, human leukocyte antigen.