Table 1.
Sociodemographic and motor data for the two groups of PD patients and the HC group.
| Pre-op (n = 21)
|
Post-op (n = 21)
|
HC (n = 21)
|
Stat. val. (F) | df | p value | |
|---|---|---|---|---|---|---|
| Mean ± SD | Mean ± SD | Mean ± SD | ||||
| Age | 59.5 ± 7.9 | 58.8 ± 7.4 | 58.2 ± 8.0 | <1 | 1. 40 | .88 |
| Disease duration | 11.0 ± 3.6 | 11.3 ± 4.1 | – | <1 | 1. 40 | .81 |
| DRT (mg) | 973.6 ± 532.3 | 828.3 ± 523.8 | – | <1 | 1. 40 | .38 |
| UPDRS III On-dopa-on-stim | – | 6.8 ± 4.3 | – | – | – | |
| UPDRS III On-dopa-off stim | 9.5 ± 6.9 | 13.7 ± 8.8 | – | 2.43 | 1. 40 | .13 |
| UPDRS III Off-dopa-on-stim | – | 14.3 ± 6.9† | – | – | – | |
| UPDRS III Off-dopa-off-stim | 27.6 ± 13.5 | 34.3 ± 8.0 | – | 2.78 | 1. 40 | .11 |
| H&Y On | 1.3 ± 0.6 | 1.3 ± 1.0 | – | <1 | 1. 40 | .86 |
| H&Y Off | 2.1 ± 0.7 | 2.3 ± 1.2 | – | <1 | 1. 40 | .67 |
| S&E On | 92.8 ± 7.8 | 84.7 ± 13.2 | – | 5.79 | 1. 40 | .02* |
| S&E Off | 74.7 ± 13.6 | 66.1 ± 21.0 | – | 2.45 | 1. 40 | .13 |
Statistical values (stat. val.), degrees of freedom (df), and p-values between preoperative (pre-op), post-operative (post-op), and HC (healthy control) groups are reported (single-factor analysis of variance).
PD = Parkinson’s disease; DRT = dopamine replacement therapy; UPDRS = Unified Parkinson’s Disease Rating Scale; H&Y = Hoehn and Yahr scale; S&E = Schwab and England scale.
†
p < .0001 when compared with the UPDRS III off-dopa-off-stim score (pairwise t-tests for two independent groups).
*
Significant if p-value < .05.