Fig. 1.

Schema showing the scope of tissue-derived ICP culture. a Intestinal cell progenitor culture, the origin of different organoids (normal and disease). b A collection of techniques and technologies that need to be in place in order to fully exploit the potential of ICP long-term cultures, for example the need for rapid genotyping to ensure the integrity of cultures from passage to passage. c The main applications and areas of ongoing research for potential deployment long-term ICP cultures in biomedical and clinical settings