Fig. 4.

Cell proliferation of human neurotypic SH-SY5Y cells following treatment with mixture of hydroxycinnamic acids (Hc acids) caffeic, vanillic, p-coumaric, and ferulic acid. SH-SY5Y cells were pre-treated without (control) or with the samples (Hc acids) and incubated for 24 h prior to treatment without or with β-amyloid (Aβ)_1-42: MTT Assay (a) and photographs of the cells at ×100 magnification using Leica DFC300FX CCD camera (b). The growth rates were estimated relative to those of the untreated cells (control) and blanks containing only the growth medium, MTT, and SDS were used to correct the absorbances. Results represent the mean ± SD of triplicate determinations. *Statistically significant (P < 0.05) difference between control and treated cells