Table 2.

Specificity and sensitivity values for each discriminant analysis and for the visual rating of AV-45 PET scans. The discriminant analyses were performed using the SUVr only (SUVr only), the histogram indexes (histogram only), and both histograms indexes and SUVr (All). Specificity, sensitivity, number of false positive (FP) and false negative (FN) are mentioned for each analysis. False positive refers to healthy controls classified as AD in the discriminant analyses or in the visual rating. False negative refers to AD patients classified as healthy controls in the discriminant analyses or in the visual ratings. The analysis leading to the best trade-off between the two measures is in bold.

	Parameters	Specificity	Sensitivity	FP	FN
SUVr	Grey SUVr only	82.4%	79.2%	3	5
	White SUVr only	35.3%	54.2%	11	7
	Grey and White SUVr only	29.4%	95.8%	12	1
Histogram indexes	Grey histogram only	88.2%	91.7%	2	2
	White histogram only	58.8%	87.5%	7	3
	Grey and White histogram only	76.5%	83.3%	4	4
SUVr and histogram indexes	Grey All	82.3%	87.5%	3	3
	White All	58.8%	83.3%	7	4
	Grey and White All	76.5%	83.3%	4	4
Visual Rating		88.2%	87.5%	2	3