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. 2016 Nov 9;6:36669. doi: 10.1038/srep36669

Table 2. A summary of changes in brain iron levels of PD patients based on the current meta-analysis.

	Postmortem			R2*			SWI
	Change	p	n	Change	p	n	Change	p	n
Substantia nigra	↑	0.01	173	↑	<10⁻⁵	631	↑	<10⁻⁴	465
Substantia nigra	↑^a	0.004	161	↑^a	<10⁻⁵	556	↑	<10⁻⁴	465
Putamen	↑	0.002	100	—	0.74	446	↑	0.04	431
Putamen	↑	0.002	100	—	0.74	446	↑^a	0.001	371
Globus pallidus	—	0.72	104	—	0.37	500	—	0.20	431
Globus pallidus	—	0.72	104	—	0.37	500	↑^a	<10⁻⁴	396
Nucleus caudatus	—	0.47	117	—	0.80	437	↑	0.0003	431
Frontal lobe	—	0.33	98	NA	NA	NA	NA	NA	NA
Temporal lobe	—	0.11	44	NA	NA	NA	NA	NA	NA
Cerebellum	—	0.14	58	NA	NA	NA	NA	NA	NA
Red nucleus	NA	NA	NA	↑	0.002	265	↑	0.02	465
Thalamus	NA	NA	NA	—	0.81	182	—	0.94	306
White matter	NA	NA	NA	—	0.07	117	—	0.93	211

^↑Increased iron level in PD.

^—No change of iron level in PD.

NA, no data available.

^aAnalyzed after heterogeneity was removed.