Table 3. The adjusted hazards ratio of risk factors of local recurrence in patients with primary GCTB around the knee.
| Risk factors | Reference | Univariate Analysis |
Multivariate Analysis |
||
|---|---|---|---|---|---|
| Unadjusted HR (95% CI) | P | Adjusted HR (95% CI) | P | ||
| Men | Women | 0.82 (0.51, 1.31) | 0.404 | ||
| Age | — | 0.98 (0.96, 1.00) | 0.068 | ||
| Left Knee | Right Knee | 0.79 (0.50, 1.26) | 0.329 | ||
| Location | Distal femur | ||||
| Proximal tibia | 1.06 (0.66, 1.70) | 0.817 | 0.81 (0.50, 1.32) | 0.400 | |
| Proximal fibular | 21.54 (4.89, 94.78) | <0.0001 | 28.52 (5.88, 138.39) | <0.0001 | |
| Campanacci grade | I | ||||
| II | 0.59 (0.26, 1.30) | 0.187 | |||
| III | 0.55 (0.26, 1.19) | 0.130 | |||
| Pathologic fracture | No | 0.66 (0.41, 1.07) | 0.092 | ||
| Surgical approach | En bloc marginal resection | ||||
| Intralesional curettage | 11.25 (4.69, 26.97) | <0.0001 | 12.07 (4.99, 29.18) | <0.0001 | |
| Curettage combined with resection | 5.85 (2.45, 13.96) | <0.0001 | 6.39 (2.66, 15.36) | <0.0001 | |
| PMMA | No | 1.16 (0.75, 1.77) | 0.516 | ||
PMMA indicated polymethylmethacrylate.