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. 2016 Jul 27;41(13):3032–3041. doi: 10.1038/npp.2016.114

Figure 2.

Figure 2

The BOLD response to dorsolateral prefrontal cortex (DLPFC) stimulation. A series of single pulses of transcranial magnetic stimulation were applied to the left DLPFC of healthy controls and cocaine users while they rested in an MRI scanner. The coil was positioned over the F3 location (red dot) of each individual based on the EEG International 10–20 system (black dots show standard positions). The brain regions that had a significantly elevated BOLD signal (red colormap) and significantly attenuated BOLD signal (blue colormap) are displayed for the controls (a), the cocaine users (b), and the cocaine users relative to the controls (c). The statistical maps for all of these comparisons arose from the same full factorial design (SPM12; Family-wise error-corrected clusters p<0.05). Only voxels that fell within those significant clusters are displayed.