Table 1. CUS Schedule.

CUS schedule for experiment 1
Day −1	Habituation to fear conditioning contexts	Day 9	Warm swim
Day 0	Fear conditioning (all groups)	Day 10	Social defeat
Day 1	Restraint	Day 11	Cold stress (begin food restriction for AST)
Day 2	Shaking/crowding	Day 12	Tail pinch
Day 3	Social defeat	Day 13	Cold swim
Day 4	Warm swim	Day 14	Cold stress
Day 5	Wet bedding	Day 15	AST habituation
Day 6	Social defeat	Day 16	AST training
Day 7	Shaking/crowding	Day 17	Extinction training (extinction groups only)
Day 8	Cold stress	Day 18	AST testing
CUS schedule for experiments 2–5
Day −1	Habituation to fear conditioning contexts	Day 9	Warm swima
Day 0	Fear conditioning (extinction groups only)	Day 10	Social defeat
Day 1	Restraint	Day 11	Footshock (begin food restriction for AST)
Day 2	Shaking/crowding	Day 12	Tail pinch
Day 3	Social defeat	Day 13	Cold swima
Day 4	Warm swima	Day 14	Cold stress
Day 5	Wet bedding	Day 15	AST habituation
Day 6	Social defeat	Day 16	AST training
Day 7	Shaking/crowding	Day 17	Extinction training or tone control treatment
Day 8	Footshock	Day 18	SPDB or AST testing

^aSwim stress was replaced by other stressors in experiment 5 to avoid infection due to surgery.