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. 2016 Nov 9;14:172. doi: 10.1186/s12916-016-0724-1

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Some drugs used to modulate gastric acid secretion and their times of introduction (earliest papers listed in PubMed); some are no longer in use; the color coding corresponds to that in Fig. 1