Table 5.
Multiple linear regression analysis of talinolol (50 mg) clearance
| Factor | r (r2)a | Coefficient | p |
|---|---|---|---|
| All factors | 0.55 (0.30) | - | <0.001 |
| Sex | 0.20 (0.04) | 0.184 | 0.044 |
| Age | 0.02 (<0.01) | 0.001 | NS |
| Body mass index | 0.20 (0.04) | 0.022 | 0.041 |
| Protein consumption | −0.20 (0.04) | −0.144 | 0.046 |
| Vegetable consumption | −0.20 (0.04) | −0.114 | 0.050 |
| MDR1 C1236T | −0.05 (<0.01) | −0.039 | NS |
| MDR1 G2677T/A | −0.03 (<0.01) | −0.020 | NS |
NS not significant. aThe correlation is given for the total model with all factors. The r2 (coefficient of determination) may indicate the fraction of the total variation explained by the respective factors