Table 2.
Summary table showing significantly up-regulated or down-regulated proteins with protein proteolysis function in SOL of Daurian ground squirrels identified by iTRAQ
| Acc no. (NCBI) | Prot name [Ictidomys tridecemlineatus] | MW (Da) | Peptide | Score | 60-d hibernation vs pre-hibernation | Post-hibernation vs pre-hibernation | Post-hibernation vs 60-d hibernation | |||
|---|---|---|---|---|---|---|---|---|---|---|
| Fold change | Sig | Fold change | Sig | Fold change | Sig | |||||
| Up-regulated proteins | ||||||||||
| gi|532073955 | proteasome subunit alpha type-6 | 28470 | 8 | 480 | 1.23 | * | 1.248 | * | ||
| gi|532105099 | proteasome subunit alpha type-5 | 30824 | 7 | 614 | 1.226 | * | 1.226 | * | ||
| gi|59800155 | 26S protease regulatory subunit 10B | 53861 | 7 | 589 | 1.281 | * | 1.264 | * | ||
| gi|532070252 | 26S proteasome non-ATPase regulatory subunit 5 isoform X1 | 63125 | 2 | 46 | 1.517 | * | ||||
| gi|532091148 | 26S proteasome non-ATPase regulatory subunit 4 | 48541 | 5 | 133 | 1.488 | * | ||||
| gi|532103645 | proteasome subunit beta type-6 isoform X1 | 27252 | 3 | 115 | 1.295 | * | ||||
| gi|532073989 | proteasome subunit alpha type-3 isoform X1 | 34727 | 5 | 462 | 1.209 | * | ||||
| gi|532066291 | cytosol aminopeptidase | 66612 | 11 | 731 | 1.202 | * | ||||
| gi|532101732 | 26S protease regulatory subunit 6B isoform X1 | 56577 | 4 | 375 | 1.246 | * | ||||
| gi|532088665 | 26S protease regulatory subunit 6A | 60713 | 9 | 638 | 1.32 | * | ||||
| gi|532080894 | calpastatin | 113441 | 7 | 179 | 1.226 | * | ||||
| gi|532073188 | endoplasmin | 117277 | 14 | 399 | 1.316 | * | ||||
| gi|532076563 | ubiquitin-like modifier-activating enzyme 1 isoform X2 | 135211 | 19 | 1304 | 1.242 | * | ||||
| gi|532069763 | xaa-Pro aminopeptidase 1-like isoform X1 | 88255 | 5 | 128 | 1.485 | * | ||||
| gi|532062055 | proteasome subunit alpha type-4 | 37964 | 6 | 247 | 1.289 | * | ||||
| gi|532114683 | calpain small subunit 1 | 31666 | 4 | 257 | 1.301 | * | 1.488 | * | ||
| gi|532105581 | ubiquitin carboxyl-terminal hydrolase 5 isoform X1 | 112519 | 10 | 369 | 1.221 | * | ||||
| gi|532082471 | acylamino-acid-releasing enzyme | 91596 | 7 | 160 | 1.567 | * | ||||
| gi|532088974 | prolyl endopeptidase | 95929 | 11 | 396 | 1.385 | * | ||||
| gi|532078165 | ubiquitin carboxyl-terminal hydrolase isozyme L3 | 30900 | 4 | 212 | 1.591 | * | 1.552 | * | ||
| gi|532097874 | ubiquitin fusion degradation protein 1 homolog isoform X1 | 41760 | 5 | 206 | 1.419 | * | ||||
| gi|532116708 | proteasome subunit beta type-1 | 30778 | 7 | 506 | 1.283 | * | ||||
| gi|532085114 | 26S proteasome non-ATPase regulatory subunit 12 isoform X1 | 66713 | 4 | 67 | 1.457 | * | ||||
| Down-regulated proteins | ||||||||||
| gi|532064840 | ubiquinone biosynthesis protein COQ9, mitochondrial | 38864 | 6 | 713 | 0.811 | * | ||||
| gi|532078642 | poly(rC)-binding protein 2 isoform X1 | 54651 | 5 | 470 | 0.732 | * | ||||
| gi|532086828 | cullin-5 | 114587 | 6 | 160 | 0.774 | * | ||||
Acc no. (Accession number), Prot name (protein name), MW (Molecular mass), Peptide (number of peptides matched), Score (Mowse score), Sig (*P-value < 0.05 was considered statistically significant)